Pesquisa | Secretaria de Estado da Saúde

1.

Human T Cell Leukemia Virus Type 1: Persistence and Pathogenesis.

Bangham, Charles R M.

Annu Rev Immunol ; 36: 43-71, 2018 04 26.

Artigo Inglês | MEDLINE | ID: mdl-29144838

2.

The impact of HTLV-1 expression on the 3D structure and expression of host chromatin.

Yaguchi, Hiroko; Melamed, Anat; Ramanayake, Saumya; Kiik, Helen; Witkover, Aviva; Bangham, Charles R M.

PLoS Pathog ; 20(3): e1011716, 2024 Mar.

Artigo Inglês | MEDLINE | ID: mdl-38427693

3.

The transcriptome of HTLV-1-infected primary cells following reactivation reveals changes to host gene expression central to the proviral life cycle.

Aristodemou, Aris E N; Rueda, David S; Taylor, Graham P; Bangham, Charles R M.

PLoS Pathog ; 19(7): e1011494, 2023 07.

Artigo Inglês | MEDLINE | ID: mdl-37523412

4.

HTLV-1 persistence and the oncogenesis of adult T-cell leukemia/lymphoma.

Bangham, Charles R M.

Blood ; 141(19): 2299-2306, 2023 05 11.

Artigo Inglês | MEDLINE | ID: mdl-36800643

5.

Dynamics and consequences of the HTLV-1 proviral plus-strand burst.

Ramanayake, Saumya; Moulding, Dale A; Tanaka, Yuetsu; Singh, Abhyudai; Bangham, Charles R M.

PLoS Pathog ; 18(11): e1010774, 2022 11.

Artigo Inglês | MEDLINE | ID: mdl-36441826

6.

Time-course of host cell transcription during the HTLV-1 transcriptional burst.

Kiik, Helen; Ramanayake, Saumya; Miura, Michi; Tanaka, Yuetsu; Melamed, Anat; Bangham, Charles R M.

PLoS Pathog ; 18(5): e1010387, 2022 05.

Artigo Inglês | MEDLINE | ID: mdl-35576236

7.

Clonality of HIV-1- and HTLV-1-Infected Cells in Naturally Coinfected Individuals.

Katsuya, Hiroo; Cook, Lucy B M; Rowan, Aileen G; Melamed, Anat; Turpin, Jocelyn; Ito, Jumpei; Islam, Saiful; Miyazato, Paola; Jek Yang Tan, Benjy; Matsuo, Misaki; Miyakawa, Toshikazu; Nakata, Hirotomo; Matsushita, Shuzo; Taylor, Graham P; Bangham, Charles R M; Kimura, Shinya; Satou, Yorifumi.

J Infect Dis ; 225(2): 317-326, 2022 01 18.

Artigo Inglês | MEDLINE | ID: mdl-33844021

8.

Evolution of retrovirus-infected premalignant T-cell clones prior to adult T-cell leukemia/lymphoma diagnosis.

Rowan, Aileen G; Dillon, Richard; Witkover, Aviva; Melamed, Anat; Demontis, Maria-Antonietta; Gillet, Nicolas A; Mun, Liew Jun; Bangham, Charles R M; Cook, Lucy B; Fields, Paul A; Taylor, Graham P.

Blood ; 135(23): 2023-2032, 2020 06 04.

Artigo Inglês | MEDLINE | ID: mdl-32160278

9.

Kinetics of HTLV-1 reactivation from latency quantified by single-molecule RNA FISH and stochastic modelling.

Miura, Michi; Dey, Supravat; Ramanayake, Saumya; Singh, Abhyudai; Rueda, David S; Bangham, Charles R M.

PLoS Pathog ; 15(11): e1008164, 2019 11.

Artigo Inglês | MEDLINE | ID: mdl-31738810

10.

The relative contributions of infectious and mitotic spread to HTLV-1 persistence.

Laydon, Daniel J; Sunkara, Vikram; Boelen, Lies; Bangham, Charles R M; Asquith, Becca.

PLoS Comput Biol ; 16(9): e1007470, 2020 09.

Artigo Inglês | MEDLINE | ID: mdl-32941445

11.

Arsenic trioxide (As₂O₃) as a maintenance therapy for adult T cell leukemia/lymphoma.

Marçais, Ambroise; Cook, Lucy; Witkover, Aviva; Asnafi, Vahid; Avettand-Fenoel, Véronique; Delarue, Richard; Cheminant, Morgane; Sibon, David; Frenzel, Laurent; de Thé, Hugues; Bangham, Charles R M; Bazarbachi, Ali; Hermine, Olivier; Suarez, Felipe.

Retrovirology ; 17(1): 5, 2020 03 21.

Artigo Inglês | MEDLINE | ID: mdl-32199462

12.

Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia.

Turpin, Jocelyn; Yurick, David; Khoury, Georges; Pham, Hai; Locarnini, Stephen; Melamed, Anat; Witkover, Aviva; Wilson, Kim; Purcell, Damian; Bangham, Charles R M; Einsiedel, Lloyd.

J Infect Dis ; 219(4): 562-567, 2019 01 29.

Artigo Inglês | MEDLINE | ID: mdl-30307560

13.

Digoxin reveals a functional connection between HIV-1 integration preference and T-cell activation.

Zhyvoloup, Alexander; Melamed, Anat; Anderson, Ian; Planas, Delphine; Lee, Chen-Hsuin; Kriston-Vizi, Janos; Ketteler, Robin; Merritt, Andy; Routy, Jean-Pierre; Ancuta, Petronela; Bangham, Charles R M; Fassati, Ariberto.

PLoS Pathog ; 13(7): e1006460, 2017 Jul.

Artigo Inglês | MEDLINE | ID: mdl-28727807

14.

Adult T-cell leukemia: genomic analysis.

Bangham, Charles R M.

Blood ; 139(7): 953-954, 2022 02 17.

Artigo Inglês | MEDLINE | ID: mdl-35175323

15.

The retrovirus HTLV-1 inserts an ectopic CTCF-binding site into the human genome.

Satou, Yorifumi; Miyazato, Paola; Ishihara, Ko; Yaguchi, Hiroko; Melamed, Anat; Miura, Michi; Fukuda, Asami; Nosaka, Kisato; Watanabe, Takehisa; Rowan, Aileen G; Nakao, Mitsuyoshi; Bangham, Charles R M.

Proc Natl Acad Sci U S A ; 113(11): 3054-9, 2016 Mar 15.

Artigo Inglês | MEDLINE | ID: mdl-26929370

16.

CADM1/TSLC1 Identifies HTLV-1-Infected Cells and Determines Their Susceptibility to CTL-Mediated Lysis.

Manivannan, Kiruthika; Rowan, Aileen G; Tanaka, Yuetsu; Taylor, Graham P; Bangham, Charles R M.

PLoS Pathog ; 12(4): e1005560, 2016 04.

Artigo Inglês | MEDLINE | ID: mdl-27105228

17.

T Cell Receptor Vß Staining Identifies the Malignant Clone in Adult T cell Leukemia and Reveals Killing of Leukemia Cells by Autologous CD8+ T cells.

Rowan, Aileen G; Witkover, Aviva; Melamed, Anat; Tanaka, Yuetsu; Cook, Lucy B M; Fields, Paul; Taylor, Graham P; Bangham, Charles R M.

PLoS Pathog ; 12(11): e1006030, 2016 Nov.

Artigo Inglês | MEDLINE | ID: mdl-27893842

18.

Erratum to: Clonality of HIV-1- and HTLV-1-Infected Cells in Naturally Coinfected Individuals.

Katsuya, Hiroo; Cook, Lucy B M; Rowan, Aileen G; Melamed, Anat; Turpin, Jocelyn; Ito, Jumpei; Islam, Saiful; Miyazato, Paola; Jek Yang Tan, Benjy; Matsuo, Misaki; Miyakawa, Toshikazu; Nakata, Hirotomo; Matsushita, Shuzo; Taylor, Graham P; Bangham, Charles R M; Kimura, Shinya; Satou, Yorifumi.

J Infect Dis ; 225(2): 359, 2022 Jan 18.

Artigo Inglês | MEDLINE | ID: mdl-34865054

19.

Rapid dissemination of human T-lymphotropic virus type 1 during primary infection in transplant recipients.

Cook, Lucy B M; Melamed, Anat; Demontis, Maria Antonietta; Laydon, Daniel J; Fox, James M; Tosswill, Jennifer H C; de Freitas, Declan; Price, Ashley D; Medcalf, James F; Martin, Fabiola; Neuberger, James M; Bangham, Charles R M; Taylor, Graham P.

Retrovirology ; 13: 3, 2016 Jan 08.

Artigo Inglês | MEDLINE | ID: mdl-26745892

20.

Clonality of HTLV-2 in natural infection.

Melamed, Anat; Witkover, Aviva D; Laydon, Daniel J; Brown, Rachael; Ladell, Kristin; Miners, Kelly; Rowan, Aileen G; Gormley, Niall; Price, David A; Taylor, Graham P; Murphy, Edward L; Bangham, Charles R M.

PLoS Pathog ; 10(3): e1004006, 2014 Mar.

Artigo Inglês | MEDLINE | ID: mdl-24626195

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Human T Cell Leukemia Virus Type 1: Persistence and Pathogenesis.

The impact of HTLV-1 expression on the 3D structure and expression of host chromatin.

The transcriptome of HTLV-1-infected primary cells following reactivation reveals changes to host gene expression central to the proviral life cycle.

HTLV-1 persistence and the oncogenesis of adult T-cell leukemia/lymphoma.

Dynamics and consequences of the HTLV-1 proviral plus-strand burst.

Time-course of host cell transcription during the HTLV-1 transcriptional burst.

Clonality of HIV-1- and HTLV-1-Infected Cells in Naturally Coinfected Individuals.

Evolution of retrovirus-infected premalignant T-cell clones prior to adult T-cell leukemia/lymphoma diagnosis.

Kinetics of HTLV-1 reactivation from latency quantified by single-molecule RNA FISH and stochastic modelling.

The relative contributions of infectious and mitotic spread to HTLV-1 persistence.

Arsenic trioxide (As₂O₃) as a maintenance therapy for adult T cell leukemia/lymphoma.

Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia.

Digoxin reveals a functional connection between HIV-1 integration preference and T-cell activation.

Adult T-cell leukemia: genomic analysis.

The retrovirus HTLV-1 inserts an ectopic CTCF-binding site into the human genome.

CADM1/TSLC1 Identifies HTLV-1-Infected Cells and Determines Their Susceptibility to CTL-Mediated Lysis.

T Cell Receptor Vß Staining Identifies the Malignant Clone in Adult T cell Leukemia and Reveals Killing of Leukemia Cells by Autologous CD8+ T cells.

Erratum to: Clonality of HIV-1- and HTLV-1-Infected Cells in Naturally Coinfected Individuals.

Rapid dissemination of human T-lymphotropic virus type 1 during primary infection in transplant recipients.

Clonality of HTLV-2 in natural infection.